The nuclear receptor 4A family members: mediators in human disease and autophagy

The nuclear receptor 4A family members: mediators in human disease and autophagy

Blog Article

Abstract The Nuclear receptor 4A (NR4A) subfamily, which belongs to the nuclear receptor (NR) superfamily, has three members: NR4A1 (Nur77), NR4A2 (Nurr1) and NR4A3 (Nor1).They are gene regulators with broad BOSCH Serie 4 BFL553MB0B Built-in Solo Microwave - Black involvement in various signaling pathways and human disease responses, including autophagy.Here, we provide a concise overview of the current understanding of the role of the NR4A subfamily members in human diseases and review the research into their regulation of cell autophagy.

A deeper understanding of these mechanisms Circle S Barrel Style Saddle has potential to improve drug development processes and disease therapy.